Collect. Czech. Chem. Commun. 1991, 56, 2175-2182
https://doi.org/10.1135/cccc19912175

Reactions of six-membered heterocyclic β-enaminonitriles with electrophilic reagents

Salem E. Zayeda, Eiman I. Abou Elmageda, Saud A. Metwallya and Mohamed H. Elnagdib

a Department of Chemistry, Faculty of Science of Quena, Assiut University, Egypt
b Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt

Abstract

The nitriles I reacted with acetylacetone and with ethyl acetoacetate to afford 2-amino-3-cyano-4H-pyran derivatives. They reacted further to yield pyranopyridine derivatives. The reaction of V with acetylacetone afforded the pyridinethione VIII. This afforded, reacting with aromatic aldehydes or with cinnamonitriles quinoline derivatives XVII.