Collect. Czech. Chem. Commun. 1990, 55, 1555-1561

Synthesis of alkenes by Wittig reaction using lithium 1,3-diaminopropane as a base

Ludvík Streinz, David Šaman, Karel Konečný and Miroslav Romaňuk

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


It has been found that the lithium 1,3-diaminopropane (X) can be used for generation of non-stabilized ylides from alkyltriphenylphosphonium salts. These ylides with aldehydes afford olefins in moderate yield with high Z-stereoselectivity. The reaction conditions were studied.