Collect. Czech. Chem. Commun. 1990, 55, 1049-1054
https://doi.org/10.1135/cccc19901049

Synthesis and reactions of 2-(2-arylvinyl) pyrimidines

Said El-Bahaie, Mohamed G. Assy and Azza Kadry

Department of Chemistry, Faculty of Science, Zagazig University, Egypt

Abstract

2-(2-Arylvinyl)-4-mercapto-5-acetylpyrimidines IIIa-IIId were synthesized by condensation of cinnamoyl isothiocyanates Ia-Id with 2-aminopent-2-ene-4-one II. The synthesis of 4-methylthio-, 4-(β-cyano)ethylthio- and 4-oxopyrimidines is also described. Compounds IV reacted with hydrazine hydrate to yield the corresponding pyrazolopyrimidine.