Collect. Czech. Chem. Commun.
1990, 55, 469-478
https://doi.org/10.1135/cccc19900469
N,N'-diphenylacetamidinium carboxylates
Jiří Krechla, Svatava Smrčkováa, Miroslav Ludwigb and Josef Kuthana
a Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6
b Department of Organic Chemistry, Institute of Chemical Technology, 532 10 Pardubice
Abstract
Various N,N'-diphenylacetamidinium carboxylates were prepared and the nature of amidinium-carboxylate interactions was examined by 1H and 13C NMR spectra. Correlation between pKa of the respective acids and 1H NMR shifts in CHCl3 is described. The compounds due to their solubility and other physico-chemical properties represent valuable models of lactate dehydrogenase active site.
