Collect. Czech. Chem. Commun. 1989, 54, 1746-1752

Application of cellulose paper as support material in simultaneous solid phase peptide synthesis

Jutta Eichler, Michael Beyermann and Michael Bienert

Institute of Drug Research, Academy of Sciences of the G.D.R., Berlin 1136, G.D.R.


Cellulose paper was esterified with Nα-Fmoc-protected amino acid chlorides providing a chemically stable segmental support, the utility of which for simultaneous solid phase peptide synthesis was demonstrated by the synthesis of several sets of model peptides following different synthetic strategies.