Collect. Czech. Chem. Commun. 1989, 54, 1346-1357

Some 2-nitromethyl-, 2,6-bis(nitromethyl)-, 2-cyano-, and 2,6-dicyano-substituted derivatives of polyalkylated 3,5-dicyano-1,4-dihydropyridines

Antonín Kurfürst and Marián Schwarz

Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6


Nitration of polyalkyated 3,5-dicyano-1,4-dihydropyridines Ia-Id to the first and second degrees has been studied leading to compounds II and III, and conversion of nitromethyl groups of these compounds into nitrile groups with formation of tricyano derivatives IV and tetracyano derivatives V has been followed. Also given is the fragmentation of the synthesized compounds II-V by an electron impact in mass spectrometer and further spectral characteristics.