Collect. Czech. Chem. Commun. 1989, 54, 1306-1310
https://doi.org/10.1135/cccc19891306

Homolytic carbamoylation and alkoxycarbonylation of 2-aminopyrazine

Tomáš Vontora, Karel Paláta and Antonín Lyčkab

a Faculty of Pharmacy, Charles University, 501 65 Hradec Králové
b Research Institute of Organic Syntheses, 532 18 Pardubice-Rybitví

Abstract

3-Amino-2-pyrazinecarboxylic acid amide and methyl and ethyl esters have been prepared by respective homolytic carbamoylation and alkoxycarbonylation. The identity of products has. been confirmed by the mass and NMR spectroscopies.