Collect. Czech. Chem. Commun. 1989, 54, 3162-3170

A comment on evaluation of effects of mixed solvents by means of the Born and Kirkwood method

Vojtěch Bekárek

Institute of Analytical and Organic Chemistry, Palacký University, 771 45 Olomouc


The evaluation of the mixed solvent effect by means of the Kirkwood and Born functions of the relative permitivity of the mixed solvent has been criticized as a thermodynamically inconsistent procedure. A procedure has been suggested to estimate the composition of solvation sphere around dipolar molecules or transition states in binary mixtures of a polar and a nonpolar solvents.