Collect. Czech. Chem. Commun. 1989, 54, 2731-2737

Synthesis and biological activity of some derivatives related to 2-methylenebutanedioic acid

Miroslav Veverkaa and Eva Kraľovičováb

a Institute of Biotechnology, Slovak Technical University, 812 37 Bratislava
b Research Institute of Chemical Technology, 831 06 Bratislava


Nucleophilic reactions of methyl 3-chloroformyl-3-butenoate with N-substituted anilines and substituted phenols, and also preparation of 2-methylenebutanedioic acid monoanilides and their dehydration to the corresponding N-arylimides are described.