Collect. Czech. Chem. Commun. 1989, 54, 206-214
https://doi.org/10.1135/cccc19890206

2-Amino-substituted derivatives of benzimidazoles from 2-isothiocyanato carboxylates

Ľubomír Flocha, Michal Uhera and Ján Leškob

a Department of Organic Chemistry, Slovak Technical University, 812 37 Bratislava
b Laboratory of Mass Spectrometry, Slovak Technical University, 812 37 Bratislava

Abstract

2-Isothiocyanato carboxylates react with o-phenylenediamine to give N,N'-substituted thioureas, which cyclize to yield 2-amino-substituted derivatives of imidazole. The structure of these compounds was corroborated by IR, UV, 1H, 13C NMR, and mass spectral methods.