Collect. Czech. Chem. Commun. 1988, 53, 1647-1654

The limit of determination and the limit of nonzero information content

Karel Eckschlager

Institute of Inorganic Chemistry, Czechoslovak Academy of Sciences, 250 68 Prague-Řež


The limit of nonzero information content, which is the lowest result of quantitative determination that is accurate and precise enough to have nonzero information content, is suggested to serve as the lowest limit of applicability of an analytical method whose results involve a systematic error. The limit of determination at which the relative precision of results is σr = 10% can be used as the lowest limit of applicability of a method whose results are accurate.