Collect. Czech. Chem. Commun. 1988, 53, 857-859

A new variant of the synthesis of disparlure via acetylenic intermediates

Jaroslav Jonas, Pavel Slanina, Otakar Humpa and Ctibor Mazal

Department of Organic Chemistry, J. E. Purkyně University, 611 37 Brno


Disparlure, the sexual feromone of the Gypsy Moth, has been prepared via the known intermediate 2-methyl-7-octadecyne, using a new constructional principle: C9 + C10 → C19. The so far undescribed 7-methyl-1-octyne was used as the C9 component. The advantages of this procedure consist in higher yields of disparlure and in a substantial simplification of the method of purification of 2-methyl-7-octadecyne.