Collect. Czech. Chem. Commun. 1988, 53, 643-645

Synthesis of 6-aryl-6H-naphtho[2’,1’:5,6]pyrano[4,3-b]-[1,8]naphthyridines

Kamreddy Rajendar Reddy, Kaleru Mogilaiah and Bathula Sreenivasulu

Department of Chemistry, Kakatiya University, Warangal 506 009, India


A series of new 6-aryl-6H-naphtho[2’,1’:5,6]pyrano[4,3-b][1,8]naphthyridines III have been synthesized by condensing 2-aminonicotinaldehyde (I) with a number of 1-hydroxy-2-naphthyl styryl ketones II in the presence of glacial acetic acid containing a catalytic amount of conc. sulphuric acid. The products have been characterized on the basis of elemental analyses and spectral data. Antibacterial activity of these compounds is negligible.