Collect. Czech. Chem. Commun.
1988, 53, 3179-3183
https://doi.org/10.1135/cccc19883179
Synthesis of some new 3-substituted-4-hydroxy-1-methyl-quinolin-2-one derivatives as potential antibacterial and antifungal agents
Margret Mansour Girgesa, Mokhtar Ayad Hannab, Hussien Mohamed Hassana and Evelin Boshra Moawada
a Chemistry Department, Mansoura Faculties of Science, Mansoura University, Mansoura, Egypt
b Chemistry Department, Damiatta Faculties of Science, Mansoura University, Mansoura, Egypt
Abstract
3-Acetyl-4-hydroxy-1-methylquinolin-2-one (I) and its bromo derivative II were allowed to react with different reagents to get new quinoline derivatives that have different heterocyclic moieties at position 3. The antibacterial and antifungal activities of the products were also evaluated.
