Collect. Czech. Chem. Commun. 1988, 53, 2787-2790
https://doi.org/10.1135/cccc19882787

New approach to the use of 2-bromoethyl esters in peptide synthesis

M. Joaquina S. A. Amaral Trigo and M. Isabel A. Oliveira Santos

Centro de investigação em Química da Universidade do Porto, Faculdade de Ciências do Porto, 4000 Porto, Portugal

Abstract

The synthesis of six new fully protected dipeptides 2-bromoethyl esters and a new method for the removal of the C-protection by the action of the sulphide anion, at room temperature, are described.