Collect. Czech. Chem. Commun. 1987, 52, 1026-1042

Alternative syntheses of 2α,3α,17β-trihydroxy-7-oxa-B-homo-5α-androstan-6-one and some androstane brassinolide analogs

Ladislav Kohouta, Václav Černýa and Miroslav Strnadb

a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
b Institute of Experimental Botany, Czechoslovak Academy of Sciences, 772 00 Olomouc


The title compound XVI was synthesized from III, IV or V. Related compounds X, XIII, XVI, XVIII, XXIII, XXIV, XXVII, XXVIII, XXXV, XXXVI, XLI, and XLIII were also prepared and tested by bean second internode bioassay. They showed only low activity (by about 2-3 orders or even lower than 24-epibrassinolide).