Collect. Czech. Chem. Commun. 1987, 52, 395-398

Ultrasound-accelerated synthesis of ferrocene-containing pyrimidine derivatives

Štefan Toma, Martin Putala and Marta Sališová

Department of Organic Chemistry, Comenius University, 842 15 Bratislava


The base-catalysed addition of thiourea to ferrocene analogues of chalcones is faster and more selective when the reaction mixture is sonicated than when merely heated. 4-Aryl-6-ferrocenyl- and 6-aryl-4-ferrocenyl-3,4-dihydropyrimidine-2(1H)-tyhiones were isolated in 58-79% yields.