Collect. Czech. Chem. Commun.
1987, 52, 2717-2721
https://doi.org/10.1135/cccc19872717
Synthesis and reactivity of methyl ester of 1'-(chloromethyl)ferrocenecarboxylic acid
Štefan Kaluz and Štefan Toma
Department of Organic Chemistry, Comenius University, 842 15 Bratislava
Abstract
The reaction of methyl ester of 1'-(hydroxymethyl)ferrocenecarboxylic acid with PCl3 afforded methyl ester of 1'-(chloromethyl)ferrocenecarboxylic acid. The reactivity of the ester with selected O, S, N and C-nucleophiles has been investigated. In all cases the high yields of the products of substitution of the chlorine of chloromethyl group were obtained.
