Collect. Czech. Chem. Commun. 1987, 52, 2589-2602

Micellar enzymology: Potentialities in applied areas (biotechnology)

Karel Martineka, Iliya V. Berezinb, Yurii L. Khmelnitskib, Natalya L. Klyachkoc and Andrei V. Levashovc

a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6, Czechoslovakia
b Institute of Biochemistry, USSR Academy of Sciences, 117 071 Moscow, U.S.S.R.
c Department of Chemistry, Moscow State University, 117 234 Moscow, U.S.S.R.


Micellar enzymology, a new trend in molecular biology, studies the catalysis by enzymes entrapped into hydrated reversed micelles of surfactants (detergents, phospholipids) in organic solvents. The effect of solubilization on enzymatic properties is briefly considered. Applications of such biocatalytic systems in fine organic syntheses, in clinical and chemical analyses, and in medicine, as well as probable future trends in biotechnology are discussed.