Collect. Czech. Chem. Commun. 1986, 51, 1710-1721

Sesquiterpenoids from Dittrichia viscosa (L.) GREUTER. Their structure and deterrent activity

Włodzimierz M. Daniewskia, Wojciech Kroszczyṅskia, Ełżbieta Błoszykb, Bohdan Drożdżb, Jan Nawrotc, Urszula Rychłewskad, Miloš Buděšínskýe and Miroslav Holube

a Institute of Organic Chemistry, Polish Academy of Sciences, Warsaw, Poland
b Department of Medicinal Plants, Academy of Medicine, Poznań, Poland
c Institute of Plant Protection, Poznań, Poland
d Department of Crystallography, A. Mickiewicz University, Poznań, Poland
e Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Prague, Czechoslovakia


In addition to the earlier described inuviscolide (II), the sesquiterpenic vachanic (V) and 2α-hydroxyisocostic (VII) acids, as well as carabron (VIII) and the so far undescribed sesquiterpenic lactone 11αH,13-dihydroconfertin were also isolated from Dittrichia viscosa (L.) GREUTER. For the last mentioned lactone the structure IX has been derived. The structure of vachanic acid (V) was confirmed by X-ray structural analysis. Compounds V to VII were tested for their deterrent (antifeedant) activity against selected insect pests living in corn stores, and they generally had a high activity.