Collect. Czech. Chem. Commun.
1986, 51, 2186-2192
https://doi.org/10.1135/cccc19862186
Synthesis and properties of 4-alkylaminomethyl and 4-alkoxymethyl derivatives of 5-methyl-2-furancarboxylic acid
Jarmila Štetinová, Adolf Jurášek, Jaroslav Kováč, Miloslava Dandárová and Oľga Rajniaková
Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava
Abstract
New β-substituted amines and ethers of the furan series (II-V) were prepared by reaction of methyl 4-bromomethyl-5-methyl-2-furancarboxylate (I) with nucleophiles such as pyrrolidine, piperidine, morpholine, N-phenylpiperazine, cyclohexylamine, 2-methylcyclohexylamine, N-ethylaniline, p-toluidine, ethanol, butanol and salicylaldehyde. The structure of the products was confirmed by their analytical and spectral data. Kovats indices I for the products were determined using gas-liquid chromatography.
