Collect. Czech. Chem. Commun. 1985, 50, 1642-1647

Interphase distribution of 2-furylethylenes

Štefan Baláža, Anton Kuchára, Ernest Šturdíka, Michal Rosenberga, Ladislav Štibrányib and Dušan Ilavskýb

a Department of Biochemical Technology
b Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava


The distribution kinetics of 35 2-furylethylene derivatives in two-phase system 1-octanol-water was investigated. The transport rate parameters in direction water-1-octanol (l1) and backwards (l2) are partition coefficient P = l1/l2 dependent according to equations l1 = logP - log(βP + 1) + const., l2 = -log(βP + 1) + const., const. = -5.600, β = 0.261. Importance of this finding for assesment of distribution of compounds under investigation in biosystems and also the suitability of the presented method for determination of partition coefficients are discussed.