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Collect. Czech. Chem. Commun. 1985, 50, 132-145
https://doi.org/10.1135/cccc19850132

Oxytocin analogues with inhibitory properties, containing in position 2 a hydrophobic amino acid of D-configuration

Michal Lebl, Tomislav Barth, Linda Servítová, Jiřina Slaninová and Karel Jošt

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6

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  • Fragiadaki Maria, Magafa Vassiliki, Borovicková Lenka, Slaninová Jiřina, Cordopatis Paul: Synthesis and biological activity of oxytocin analogues containing conformationally-restricted residues in position 7. Eur J Med Chem 2007, 42, 799. <https://doi.org/10.1016/j.ejmech.2006.12.016>
  • Manning Maurice, Cheng Ling Ling, Stoev Stoytcho, Wo Nga Ching, Chan W. Y, Szeto Hazel H., Durroux Thierry, Mouillac Bernard, Barberis Claude: Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban. J. Peptide Sci. 2005, 11, 593. <https://doi.org/10.1002/psc.667>
  • Slaninová Jiřina, Maletínská Lenka, Vondrášek Jiří, Procházka Zdenko: Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. Journal of Peptide Science 2001, 7, 413. <https://doi.org/10.1002/psc.334>
  • Manning Maurice, Stoev Stoytcho, Cheng Ling Ling, Ching Wo Nga, Chan W.Y.: Design of Oxytocin Antagonists, which are more Selective than Atosiban. Journal of Peptide Science 2001, 7, 449. <https://doi.org/10.1002/psc.339>
  • Procházka Zdenko, Žertová Miroslava, Slaninová Jiřina: The analogs of oxytocin and D-homoarginine vasopressin with bulky substituted phenylalanine in position 2. Lett Pept Sci 2000, 7, 179. <https://doi.org/10.1007/BF02443586>
  • MANNING M., MITEVA K., PANCHEVA S., STOEV S., WO N.C., CHAN W.Y.: Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with Atosiban. International Journal of Peptide and Protein Research 1995, 46, 244. <https://doi.org/10.1111/j.1399-3011.1995.tb00596.x>
  • MAJER PAVEL, SLANINOVÁ JIŘINA, LEBL MICHAL: Synthesis of methylated phenylalanines via hydrogenolysis of corresponding 1,2,3,4‐tetrahydroisoquinoline‐3‐carboxylic acids. International Journal of Peptide and Protein Research 1994, 43, 62. <https://doi.org/10.1111/j.1399-3011.1994.tb00376.x>
  • LEBL MICHAL, TOTH GEZA, SLANINOVÁ JIŘINA, HRUBY VICTOR J.: Conformationally biased analogs of oxytocin. International Journal of Peptide and Protein Research 1992, 40, 148. <https://doi.org/10.1111/j.1399-3011.1992.tb01463.x>
  • LEBL MICHAL, HILL PATRICIA, KAZMIERSKI WIESLAW, KÁRÁSZOVÁ LENKA, SLANINOVÁ JIŘINA, FRIČ IVO, HRUBY VICTOR J.: Conformationally restricted analogs of oxytocin; stabilization of inhibitory conformation†. International Journal of Peptide and Protein Research 1990, 36, 321. <https://doi.org/10.1111/j.1399-3011.1990.tb01289.x>