Collect. Czech. Chem. Commun. 1984, 49, 1412-1420

Synthesis of sanguinarine, chelerythrine, and oxysanguinarine

Jan Šmidrkal

Research Institute of Fat Industry, 269 01 Rakovnik


Benzo[c]phenanthridines Va and Vb have been prepared by photocyclization of amines IVa and IVb and transformed into the alkaloids sanguinarine (VIa) and chelerythrine (VIb). Oxysanguinarine (XIV) has been prepared from diazoketone XVIII.