Collect. Czech. Chem. Commun. 1984, 49, 976-983

Synthesis and properties of some derivatives of 3,4-dihydro-3-oxo-2-quinoalinylacetic acid

Jaromír Toman and Jiří Klicnar

Department of Organic Chemistry, Institute of Chemical Technology, 532 10 Pardubice


The paper describes opening of isoxazole ring with 1,2-diaminobenzene leading to 2-cyanomethylene-3-oxo-1,2,3,4-tetrahydroquinoxaline and preparation of its derivatives. Synthesis have been studied of substituted 3,4-dihydro-3-oxo-quinoxaline-oxides, and tautomers of 1-oxides of 2-ethoxycarbonylmethylquinoxalines have been obtained.