Collect. Czech. Chem. Commun.
1984, 49, 2309-2314
https://doi.org/10.1135/cccc19842309
A new approach to 5H-pyrano[2,3-d]pyrimidine derivatives
Štefan Marchalín and Josef Kuthan
Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
Reaction of 2-amino-3,5-dicyano-4H-pyran derivative I with triethoxymethane gives the corresponding 2-ethoxymethyleneamino derivative II which reacts with amines RNH2 to give 5H-pyrano[2,3-d]pyrimidines of general formula III. Spectral characteristics of compounds IIIa - IIIg are discussed.