Collect. Czech. Chem. Commun. 1984, 49, 295-300

Synthesis of 2-(S-aryloxycarbonylthio)ethyl isothiocyanates - Analogues of natural mustard oils

Pavol Kristian and Jozef Gonda

Department of Organic Chemistry and Biochemistry, P. J. Šafárik University, 041 67 Košice


A simple reaction of 2-aryloxythiazolines with thiophosgene leads to formation of 2-(S-aryloxycarbonylthio)ethyl isothiocyanates. The starting thiazolines can easily be obtained from 2-bromoethyl isothiocyanates and phenolates. The structure of the products synthesized was evidenced by spectral methods.