Collect. Czech. Chem. Commun. 1983, 48, 2118-2129

Synthon approach and graph grammar

Vladimír Kvasnička

Department of Mathematics, Slovak Institute of Technology, 812 37 Bratislava


The Corey's synthon approach is formalized by a special type of graph grammar. The graph language induced by this grammar is composed of all possible graphs (molecules) that can be constructed from the so-called starting graphs. The retro-synthetic analysis is treated as the parser which provides an answer to the question „is a graph element of the given language?".