Collect. Czech. Chem. Commun. 1983, 48, 1891-1897

Synthesis of pyridinium and picolinium salts of 5-nitro-2-vinylfuran having antibacterial properties

Daniel Végha, Jaroslav Kováča, Miloslava Dandárováa, Vladimír Briša and Milan Semanb

a Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava
b Institute of Molecular and Subcellular Biology, Comenius University, 821 08 Bratislava


Quaternization of pyridine, 2-, 3-, or 4-picoline with (Z)-, or (E)-5-nitro-2-furylvinyl bromide is described and the addition-elimination mechanism of the nucleophilic substitution to yield the respective (Z)-, or (E)-vinylammonium salts is discussed.