Collect. Czech. Chem. Commun. 1983, 48, 3567-3574

Heterocycles with a pyrido[3,2-e]-1,3-selenazine and pyrido[3,4-e]-1,3-selenazine ring systems

Pavol Kristian, Dušan Koščík and Jozef Gonda

Department of Organic Chemistry and Biochemistry, P. J. Šafárik University, 041 67 Košice


2-Chloronicotinoyl isoselenocyanate (IIa) and 2,6-dimethyl-4-chloronicotinoyl isoselenocyanate (IIb) react with arylamines to give 2-arylimino-4-oxopyrido[3,2-e]-1,3-selenazines IV and 2-arylimino-5,7-dimethyl-4-oxopyrido[3,4-e]-1,3-selenazines V. A reaction of IIa,b with sodium hydrogen sulfide and hydroselenide afford the respective 2-thio- and 2-seleno-4-oxopyrido-1,3-selenazines VI and VII. Structure of these new types of heterocycles was corroborated by spectral (IR, UV, 1H NMR, 13C NMR, and mass) means.