Collect. Czech. Chem. Commun. 1983, 48, 3112-3122

Synthesis and spectral properties of 4-substituted 2,6-bis-(4-biphenylyl)-3,5-dicyano-1,4-dihydropyridines

Štefan Marchalín and Josef Kuthan

Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6


Cyclocondensation of 3-amino-3-(4-biphenylyl)acrylonitrile (Ie) with benzaldehydes p-RC6H4.CHO, 2-furaldehyde and acetone produces 1,4-dihydropyridine derivatives IIa-IIj, III, and IV. 4-Cyanobiphenyl (Id) has been prepared and transformed into nitrile Ie by action of sodium powder and acetonitrile. Relation between structure and spectral properties of the dihydro derivatives prepared is discussed.