Collect. Czech. Chem. Commun.
1982, 47, 1757-1761
https://doi.org/10.1135/cccc19821757
2-Acylated derivatives of ergoline
Jan Beneš and Jiří Křepelka
Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3
Abstract
Reactions of ergoline derivatives Ia-VIIa with anhydrides of low-molecular-weight aliphatic acids, catalysed by boron trifluoride etherate, gave 2-acylated derivatives Ib-Id, IIb-IId, IIIb-Vb, or 1,2-diacylated derivatives VIb and VIIb. The compound IIb exhibited a hypotensive effect.
