Collect. Czech. Chem. Commun. 1982, 47, 755-765

First reaction steps and intermediates of the oxidation of ascorbic acid by dioxygen. Catalysis by cobalt(II) tetrasulphophthalocyanine

Dana M. Wagnerováa, Jürgen Blanckb and Josef Vepřek-Šiškaa

a Institute of Inorganic Chemistry, Czechoslovak Academy of Sciences, 160 00 Prague 6
b Central Institute of Molecular Biology, Academy of Sciences of the German Democratic Republic, 1115 Berlin - Buch, GDR


The oxidation of ascorbic acid by dioxygen catalyzed by cobalt(II) tetrasulphophthalocyanine (CoTSP) has been studied by the stopped-flow method. Two reactive intermediates, [O2.CoTSP. ascorbic acid] and [O2.CoTSP], characterized by separate absorption bands at 570 nm and 634 nm, respectively, have been proved to form in the reaction. The individual steps of the reaction have been elucidated, and their rate constants have been determined or estimated.