Collect. Czech. Chem. Commun. 1982, 47, 3306-3311
https://doi.org/10.1135/cccc19823306

Synthesis of optically active 4,4- and 5,5-disubstituted 4,5-dihydro-6H-canthin-6-ones and their CD spectra

Josef Hájíček and Jan Trojánek

Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3

Abstract

Synthesis of several optically active 4,4- and 5,5-disubstituted 4,5-dihydro-6H-canthin-6-ones ((R)-(+)-VII, (S)-(-)-XII and (R)-(+)-XVIII) and 5,5-disubstituted 4,5-dihydro-6H-canthin-4,6-diones ((S)-(-)-XIX and (R)-(+)-XX) is described and CD spectra of these compounds are discussed.