Collect. Czech. Chem. Commun. 1982, 47, 3013-3018

Mass transfer in heterogeneous system enzyme-substrate; Approximate analytical model for the case of liquid substrate-immobilized enzyme

František Kaštáneka, Jindřich Zahradníka and Germanico Ocampob

a Institute of Chemical Process Fundamentals, Czechoslovak Academy of Sciences, 165 02 Prague 6-Suchdol, Czechoslovakia
b Instituto Cubano de Investigaciones de los Derivados de la Cana de Azucar, La Habana, Cuba


Calculation procedure is suggested for flow intensity of substrate toward reaction interface of immobilized enzyme at simultaneous effect of enzymatic reaction and internal diffusion. The approximate model is presented in an analytical form for the basic type of Michaelis-Menten kinetics and for the case of inhibition in excess of substrate.