Collect. Czech. Chem. Commun. 1981, 46, 926-932

Alkaloids from Papaver oreophilum F. J. RUPR

František Věžník, Eva Táborská and Jiří Slavík

Department of Medical Chemistry and Biochemistry, Purkyně University, 662 43 Brno


In addition to the konwn alkaloids from Papaver oreophilum F. J. RUPR., i.e. oridine, mecambridine, isocorydine, protopine, oreodine, rhoeadine, nuciferine, isooridine (oridine-2), oridine-3, alkaloid PO-5 (R-K, alborine) and trace alkaloids rhoeagenine, oreogenine, isorhoeadine, papaverrubines A, D and E, sanguinarine, N-methyloridine and coptisine, we isolated from the aerial part or from the roots the following further alkaloids: allocryptopine and - from the quaternary fraction - menisperine and magnoflorine (3.6%), which is the main alkaloid in the roots. Further corydine and trace amounts of papaverrubine C, chelirubine, berberine, corysamine and probably O-methyloridine and O,N-dimethyloridine were also detected. It was shown that oridine-3 was identical with the hydrochloride of isooridine.