Collect. Czech. Chem. Commun. 1981, 46, 2428-2434
https://doi.org/10.1135/cccc19812428

Addition-cyclization reactions of 2-pyridyl isothiocyanate

Miroslav Marchalín, Jan Světlík and Augustin Martvoň

Research Institute for Drugs, 801 00 Bratislava

Abstract

Addition-cyclization reactions of 2-pyridyl isothiocyanate with enamines and C-acids afforded derivatives containing pyrido[1,2-a]pyrimidine skeleton. Cyclization with a series of phenylhydrazones gave substituted triazolidines. The IR, UV, 1H NMR and 13C NMR spectra of the synthesized compounds are discussed.