Collect. Czech. Chem. Commun. 1980, 45, 2360-2363

The reaction of 2-cyano-3-(5-phenylsulphonyl-2-thienyl) acronitrile with nucleophiles

Rudolf Kada, Viera Knoppová, Jaroslav Kováč and Miroslav Balag

Department of Organic Chemistry, Slovak Institute of Technology, 880 37 Bratislava


5-Phenylsulphonyl- and 5-phenylthio-2-thiophenaldehydes react with malononitrile and methyl cyanoacetate under the conditions of Knoevenagel reaction to give the corresponding condensation products. It has been found that when 2-cyano-3-(5-phenylsulphonyl-2-thienyl)-acrylonitrile is treated with nucleophiles the phenylsulphonyl group is substituted.