Collect. Czech. Chem. Commun. 1980, 45, 1820-1825

Preparation of cycloheptanols symmetrically labelled with deuterium

František Tureček

J. Heyrovský Institute of Physical Chemistry and Electrochemistry, Czechoslovak Academy of Sciences, 121 38 Prague 2


Cycloheptanols labelled symmetrically with deuterium in inaccessible positions were prepared by multistep syntheses. The key intermediates of the syntheses were the corresponding labelled octanedioic acids. The method of two-phase oxidation of olefins to carboxylic acids was modified so that it would be utilizable for the preparation of dicarboxylic acids.