Collect. Czech. Chem. Commun. 1980, 45, 1662-1668

Polarographic reduction of 3-O-methylpyridoxal 5'-phosphate

Enrique López-Cantareroa, Juan Llora and Manuel Cortijob

a Departamento de Quimica-Fisica, Facultad de Ciencias de la Universidad de Granada
b Departamento de Investigaciones Quimicas (Centro Coordinado del C.S.I.C.), Granada, Spain


The polarographic reduction of 3-O-methyl-pyroxidal 5'-phosphate has been studied as a function of pH. The reduction of the aldehyde group by a two electrons process occurs in all conditions studied. The rate of interconversion between the free and hydrate forms of the carbonyl group has been computed. This reaction is acid-base catalyzed. The other reactions (proton transfers) that precede the electrodic reaction are very much faster. The results are compared with those previously obtained for pyridoxal 5'-phosphate.