Collect. Czech. Chem. Commun. 1980, 45, 1485-1494

Medium effect on alkaline hydrolysis of diphenic acid monomethyl ester

Ján Benko and Vladislav Holba

Department of Physical Chemistry, Comenius University, 816 50 Bratislava


The alkaline hydrolysis of diphenic acid monomethyl ester was studied in mixtures of water with methyl alcohol, ethyl alcohol, propyl alcohol, isopropyl alcohol, tert-butyl alcohol, and acetone. The dependences of the rate constant on the concentration of the nonaqueous component at different temperatures were obtained and the activation parameters at an isodielectric composition of the reaction medium were determined. The influence of the ionic strength on the reaction rate in the mentioned media was studied and conclusions were drawn as to the role of specific interactions between the reacting ions in the kinetics and mechanism of the studied reaction.