Collect. Czech. Chem. Commun. 1980, 45, 548-558

Oxynemorensine, an alkaloid from Senecio nemorensis L., var. subdecurrens GRISEB

Antonín Kláseka, Petr Sedmerab, Jindřich Vokounb, Anna Boevac, Svatava Dvoráčkovád and František Šantavýd

a Department of Leather Technology, Faculty of Technology, Technical University, 762 72 Gottwaldov
b Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20 Prague
c Faculty of Pharmacy, University of Sofia, 1000 Sofia, Bulgaria
d Institute of Chemistry, Medical Faculty, Palacký University, 775 15 Olomouc


From S. nemorensis L., var. subdecurrens GRISEB. there were isolated the previously obtained alkaloids nemorensine (I), retroisosenine (II), bulgarsenine (III) and, in addition, the alkaloid oxynemorensine which was assigned the structure VIII on the basis of the interpretation of the 1H-NMR, 13C-NMR, mass spectra, and on that of the identification of the products of hydrolysis and reduction. Furthermore, the isolation of the cis-nemorensic acid (V) as well as that of the unsaturated acid IV, and the transformation of bulgarsenine (III) to nemorensine (I) were described.