Collect. Czech. Chem. Commun.
1980, 45, 3370-3377
https://doi.org/10.1135/cccc19803370
N-alkylation of 3,5-dicyano-2,4,4,6-tetramethyl-1,4-dihydropyridine with some α,ω-dihalogeno-N-alkenes
Jaroslav Paleček, Jaroslav Kopecký and Josef Kuthan
Department of Organic Technology, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
Bis-1,4-dihydropyridine derivatives Vc-Vf can be obtained on reaction of α,ω-diiodo-n-alkanes with the sodio derivative II of compound I, while α,ω-dibromo-n-alkanes give a mixture of compounds Vc-Vf and IVc-IVf. Analogous products IVa and Va,b could not be prepared, owing to the predominating and disturbing elimination reactions. Spectral characteristics (UV, IR, NMR and mass spectra) of the compounds obtained are confronted with their structure.
