Collect. Czech. Chem. Commun. 1980, 45, 2949-2957

Reactions of ethyl 2-(4-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylate

Alžbeta Krutošíková, Jaroslav Kováč, Mária Chudobová and Dušan Ilavský

Department of Organic Chemistry, Slovak Institute of Technology, 880 37 Bratislava


Reduction, hydrolysis, N-alkylation and N-acylation of 2-(chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylate are described. The HMO method was used to calculate compounds I, II, IV and X as model substances furo[3,2-b]pyrrole, 2-phenylfuro[3,2-b]pyrrole and methyl furo[3,2-b]pyrrole-5-carboxylate. The stability and reactivity of the synthesized compounds are discussed on the basis of indexes of chemical reactivity.