Collect. Czech. Chem. Commun.
1979, 44, 2417-2420
https://doi.org/10.1135/cccc19792417
Kinetics of nucleophilic displacement of 2,5-disubstituted furans
Viera Knoppová, Rudolf Kada and Jaroslav Kováč
Department of Organic Chemistry, Slovak Institute of Technology, 880 37 Bratislava
Abstract
5-Nitro- and 5-bromo-2-furfurylidenemalonitriles react with secondary saturated amines in an SN reaction to replace bromo or nitro groups. The effects of nucleophilic reagent, solvent and temperature on the reaction rate were investigated. The results were contrasted with kinetic data of the SN reaction of 5-(4-X-phenylsulfonyl- or phenylthio)-2-furfurylidenemalonitriles.
