Collect. Czech. Chem. Commun.
1979, 44, 1645-1650
https://doi.org/10.1135/cccc19791645
Esters of adenosine 5'-phosphate with lipoid hydroxy compounds (adenosine nucleolipids) and their effects on the activity of enzymes of cyclic AMP system
Sixtus Hyniea and Jiří Smrtb
a Institute of Pharmacology, Faculty of General Medicine, Charles University, 128 00 Prague 2
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
Esters of adenosine 5'-phosphate with lipoid hydroxy compounds exhibit strong inhibitory effect on adenylate cyclase activity. The activities of cyclic AMP phosphodiesterase and protein kinase are moderately inhibited.
