Collect. Czech. Chem. Commun. 1979, 44, 589-592

Synthesis of 6-aminohexyl esters of uridine nucleotides

Jiří Smrt

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


6-Aminohexyl esters of uridine 3'-phosphate (V) and uridine 5'-phosphate (VI) were prepared by condensation of 6-trifluoroacetamidohexanol (IV) with pyridinium salts of the protected corresponding phosphates by means of N,N'-dicyclohexylcarbodiimide followed by removal of protecting groups.