Collect. Czech. Chem. Commun.
1979, 44, 3133-3136
https://doi.org/10.1135/cccc19793133
[1-β-Mercaptopropionic acid, 8-α-amino-β-glycylaminopropionic acid]vasopressin. A vasopressin analog with an isopeptide structure in its molecule
Milan Zaorala, Viktor Krchňáka, Jana Škopkováa and Alena Machováb
a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
b Research Institute for Pharmacy and Biochemistry, 190 00 Prague 9
Abstract
[1-β-Mercaptopropionic acid, 8-α-amino-β-glycylaminopropionic acid]vasopressin (II) was prepared by solid-phase peptide synthesis. II has an antidiuretic effect of considerable magnitude (435 I.U./mg) and specificity.
