Collect. Czech. Chem. Commun. 1975, 40, 1403-1410
https://doi.org/10.1135/cccc19751403

Thermal decomposition of 10,11-methylenedioxy-3,4,12-trimethoxy-7,8,13,13a-tetrahydro-5H-isoindolo[1,2-b] [3]benzazepine methohydroxide

Z. Veselý, J. Holubek, H. Kopecká and J. Trojánek

Individual author index pages


Other CCCC articles of these authors

  • K. Šindelář, J. Holubek and M. Protiva
    Noncataleptic neuroleptics: New approaches to the synthesis of 2-chloro-10-(4-methylpiperazino) and -10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1977, Vol. 42, Issue 12, pp. 3605–3627 [Abstract]
  • Z. J. Vejdělek, J. Holubek, M. Bartošová and M. Protiva
    4-(Aminomethyl)-s-hydrindacenes and 4,8-bis(aminomethyl)-s-hydrindacenes; Synthesis and pharmacological screening
    1977, Vol. 42, Issue 10, pp. 3094–3103 [Abstract]
  • K. Šindelář, J. Holubek, A. Dlabač, M. Bartošová and M. Protiva
    Noncataleptic potential neuroleptics: 2-Nitro and 2-hydroxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1977, Vol. 42, Issue 7, pp. 2231–2239 [Abstract]
  • I. Červená, K. Šindelář, Z. Kopicová, J. Holubek, E. Svátek, J. Metyšová, M. Hrubantová and M. Protiva
    Fluorinated tricyclic neuroleptics: 6,7-Difluoro derivative of chlorprothixene and 2-fluoro-3-hydroxy derivative of octoclothepin
    1977, Vol. 42, Issue 6, pp. 2001–2017 [Abstract]
  • V. Zikán, M. Semonský, B. Kakáč, J. Holubek and K. Řežábek
    Reaction of β-4-alkoxybenzoyl-β(α)-bromoacrylic acids and of their esters with sodium methylate and ethylate
    1977, Vol. 42, Issue 5, pp. 1562–1570 [Abstract]
  • Z. J. Vejdělek, B. Kakáč, J. Holubek, E. Svátek, M. Bartošová and M. Protiva
    1,2,3,4,7,8-Hexahydro-6H-cyclopent[g]isoquinoline and N-substituted derivatives; Synthesis and pharmacological screening
    1977, Vol. 42, Issue 4, pp. 1200–1208 [Abstract]
  • K. Šindelář, J. Metyšová, J. Holubek, Z. Šedivý and M. Protiva
    Potential oral neuroleptics with protracted action: 8-Chloro-3,7-difluoro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and further 3,7-substituted octoclothepin and dehydroclothepin derivatives
    1977, Vol. 42, Issue 4, pp. 1179–1199 [Abstract]
  • R. Smrž, J. O. Jílek, B. Kakáč, J. Holubek, E. Svátek, M. Bartošová and M. Protiva
    2(8)-Chloro-10(11)-(dimethylaminoalkyl)dibenzo[b,f]thiepins as potential CNS agents; Synthesis and pharmacological screening
    1976, Vol. 41, Issue 11, pp. 3420–3436 [Abstract]
  • V. Zikán, B. Kakáč, J. Holubek, H. Veselá and M. Semonský
    Some amides of β-4-pentoxybenzoyl-β-bromoacrylic acid
    1976, Vol. 41, Issue 10, pp. 3113–3118 [Abstract]
  • V. Zikán, M. Semonský, H. Škvorová, B. Kakáč, J. Holubek and H. Veselá
    Synthesis and saponification of ethyl esters of cis- and trans-β-4-alkoxybenzoyl-β- and -α-bromoacrylic acids
    1976, Vol. 41, Issue 10, pp. 3106–3112 [Abstract]
  • R. Smrž, J. O. Jílek, K. Šindelář, B. Kakáč, E. Svátek, J. Holubek, J. Grimová and M. Protiva
    5(or 4)-Arylthio-2-methylthiopyrimidines as potential intermediates in the synthesis of tricyclic pyrimido systems
    1976, Vol. 41, Issue 9, pp. 2771–2787 [Abstract]
  • K. Šindelář, B. Kakáč, J. Holubek, E. Svátek, M. Ryska, J. Metyšová and M. Protiva
    Potential metabolites of neuroleptics of the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series: 2,3-Dihydroxy derivatives of perathiepin and octoclothepin and some related compounds
    1976, Vol. 41, Issue 5, pp. 1396–1415 [Abstract]
  • K. Šindelář, J. O. Jílek, V. Bártl, J. Metyšová, B. Kakáč, J. Holubek, E. Svátek, J. Pomykáček and M. Protiva
    Neuroleptics of the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series and related substances: Piperazine-alkylated homologues of octoclothepin and methiothepin, 5,5-dimethyl-10,11-dihydro-5H-dibenzo[b,f]silepin analogue of perathiepin
    1976, Vol. 41, Issue 3, pp. 910–922 [Abstract]
  • I. Červená, J. Metyšová, E. Svátek, B. Kakáč, J. Holubek, M. Hrubantová and M. Protiva
    Potent neuroleptics with prolonged activity and diminished toxicity: 7,8-Dihalogeno-10-piperazinodibenzo[b,f]thiepins
    1976, Vol. 41, Issue 3, pp. 881–905 [Abstract]
  • K. Šindelář, A. Dlabač, B. Kakáč, E. Svátek, J. Holubek, Z. Šedivý, E. Princová and M. Protiva
    Noncataleptic potential neuroleptics: 2-Acetamido-, 2-amino- and 2-acetyl derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1975, Vol. 40, Issue 9, pp. 2649–2666 [Abstract]
  • K. Šindelář, A. Dlabač, J. Metyšová, B. Kakáč, J. Holubek, E. Svátek, Z. Šedivý and M. Protiva
    Potential antipsychotics: 2-Methoxy, 2-methylthio-, 2-(dimethylsulfamoyl)- and 2-trifluoromethyl-10-piperazinodibenzo[b,f]thiepins
    1975, Vol. 40, Issue 6, pp. 1940–1959 [Abstract]
  • J. Trojánek, Z. Koblicová, Z. Veselý, V. Suchan and J. Holubek
    Thermal decomposition of narceine imide methohydroxide
    1975, Vol. 40, Issue 3, pp. 681–694 [Abstract]
  • K. Bláha, Z. Koblicová and J. Trojánek
    Chiroptical properties of the 5,16-cyclocorynane type alkaloids
    1974, Vol. 39, Issue 11, pp. 3168–3176 [Abstract]
  • K. Bláha, Z. Koblicová and J. Trojánek
    Chiroptical investigations on the iboga and voacanga alkaloids
    1974, Vol. 39, Issue 8, pp. 2258–2266 [Abstract]
  • K. Šindelář, J. Metyšová, B. Kakáč, J. Holubek, E. Svátek, J. O. Jílek, J. Pomykáček and M. Protiva
    8-Acyl derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1974, Vol. 39, Issue 8, pp. 2099–2114 [Abstract]
  • K. Šindelář, B. Kakáč, E. Svátek, J. Holubek, M. Rajšner, J. Metyšová and M. Protiva
    9-Chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and some related synthetic experiments
    1974, Vol. 39, Issue 1, pp. 333–354 [Abstract]
  • K. Šindelář, M. Rajšner, I. Červená, V. Valenta, J. O. Jílek, K. Kakáč, J. Holubek, E. Svátek, F. Mikšík and M. Protiva
    Neurotropic and psychotropic agents. LXVII. 1-[4,4-Bis(4-fluorophenyl)butyl]-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine and related compounds: New synthetic approaches
    1973, Vol. 38, Issue 12, pp. 3879–3901 [Abstract]
  • K. Šindelář, B. Kakáč, E. Svátek, J. Holubek, J. Metyšová, M. Hrubantová and M. Protiva
    Neurotropic and psychotropic agents. LXVI. 6,8-Dichloro- and 6,9-dichloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1973, Vol. 38, Issue 11, pp. 3321–3338 [Abstract]
  • K. Bláha and J. Trojánek
    On alkaloids. XXVI. Chiroptical properties of 2-acylindole alkaloids, the subgroup of 5,16-cyclo-3,4-secocorynane
    1973, Vol. 38, Issue 3, pp. 929–933 [Abstract]
  • M. Kuchař, B. Kakáč, O. Němeček, E. Kraus and J. Holubek
    The kinetics of Wittig's reaction of α-ethoxycarbonylalkylidenephosphoranes with aromatic aldehydes
    1973, Vol. 38, Issue 2, pp. 447–454 [Abstract]
  • J. O. Jílek, K. Šindelář, J. Pomykáček, O. Horešovský, K. Pelz, E. Svátek, B. Kakáč, J. Holubek, J. Metyšová and M. Protiva
    Neurotropic and psychotropic compounds. LV. New syntheses of 8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and related compounds
    1973, Vol. 38, Issue 1, pp. 115–131 [Abstract]
  • M. Protiva, V. Seidlová, E. Svátek, B. Kakáč and J. Holubek
    Benzocycloheptenes and heterocyclic analogues as potential drugs. IV. Amines derived from 4-phenyl-8-chloro-2,3,4,5-tetrahydro-1-benzoxepin
    1972, Vol. 37, Issue 6, pp. 2081–2090 [Abstract]
  • K. Bláha, Z. Koblicová, J. Pospíšek and J. Trojánek
    Absolute configuration of the alkaloid brevicolline
    1971, Vol. 36, Issue 10, pp. 3448–3454 [Abstract]
  • J. O. Jílek, V. Seidlová, K. Pelz, B. Kakáč, J. Holubek, E. Svátek, Z. Šedivý and M. Protiva
    Neurotropic and psychotropic compounds. XLVIII. Several derivatives of phenanthrene, acenaphthene; anthracene and naphthalene
    1971, Vol. 36, Issue 9, pp. 3300–3313 [Abstract]
  • J. O. Jílek, J. Holubek, J. Pomykáček and M. Protiva
    Neurotropic and psychotropic compounds. XLVI. Several derivatives of cyclohexylphenyl sulfide
    1971, Vol. 36, Issue 8, pp. 2824–2830 [Abstract]
  • Z. J. Vejdělek, V. Trčka, M. Vaněček, B. Kakáč and J. Holubek
    Ganglionic blocking agents. XV. Synthesis and activity of some tertiary hexylamines
    1970, Vol. 35, Issue 9, pp. 2810–2830 [Abstract]
  • J. L. Kaul, J. Trojánek and Ajay K. Bose
    On alkaloids. XXIII. The structure of majoridine, an alkaloid from Vinca major L. var. major
    1970, Vol. 35, Issue 1, pp. 116–123 [Abstract]
  • J. Pospíšek, Z. Veselý and J. Trojánek
    Steroid derivatives. LXV. A practical preparation of 3-ketosteroids of 5α-androstane and 5α-pregnane series
    1969, Vol. 34, Issue 11, pp. 3632–3637 [Abstract]
  • Z. Veselý, J. Pospíšek and J. Trojánek
    Steroid derivatives. LXIII. Kinetics of alkali hydrolysis in 70% dioxane of acetates, propionates and butyrates of some steroid alcohols
    1969, Vol. 34, Issue 6, pp. 1801–1806 [Abstract]
  • K. Bláha, Z. Koblicová and J. Trojánek
    On alkaloids. XXI. Optical rotatory dispersion of (+)-eburnamenine and related compounds
    1969, Vol. 34, Issue 2, pp. 690–694 [Abstract]
  • Z. Veselý, J. Pospíšek and J. Trojánek
    Steroid derivatives. LIX. Kinetics of alkali hydrolysis of some testosterone esters in 70% dioxane
    1969, Vol. 34, Issue 2, pp. 685–689 [Abstract]
  • Z. Veselý, J. Holubek and J. Trojánek
    Steroid derivatives. LVII. Oxidation of cyclic ethylenedithioketals of androstane series
    1968, Vol. 33, Issue 12, pp. 4047–4053 [Abstract]
  • K. Bláha, K. Kavková, Z. Koblicová and J. Trojánek
    On alkaloids. XX. Absolute configuration of alkaloids of the eburnane series; Optical rotatory dispersion
    1968, Vol. 33, Issue 11, pp. 3833–3847 [Abstract]
  • J. Trojánek, Z. Koblicová and K. Bláha
    On alkaloids. XIX. Absolute configuration of vincamine and some related alkaloids; Optical rotatory dispersion
    1968, Vol. 33, Issue 9, pp. 2950–2961 [Abstract]
  • B. Pelc, J. Holubek, T. Wittstruck and E. Caspi
    Steroid derivatives. LIV. Friedel-Crafts acetylation of 3-acetoxy-1-methylestra-1,3,5(10),6-tetraenes
    1968, Vol. 33, Issue 4, pp. 1131–1142 [Abstract]
  • J. Pospíšek, Z. Veselý and J. Trojánek
    Steroid derivatives. LI. Reductive elimination of vinyl halogen in androstane series
    1968, Vol. 33, Issue 1, pp. 76–82 [Abstract]
  • B. Pelc, J. Hodková and J. Holubek
    Steroid derivatives. XXXVIII. Preparation of 1α,2α-oxides of androstane derivatives and their reactions
    1966, Vol. 31, Issue 3, pp. 1363–1370 [Abstract]
  • O. Exner and J. Holubek
    Acyl derivatives of hydroxylamine. XI. Study of hydroxamic acids dissociation by means of UV-spectroscopy
    1965, Vol. 30, Issue 4, pp. 940–951 [Abstract]
  • B. K. Moza, J. Trojánek, V. Hanuš and L. Dolejš
    On alkaloids. XIII. On the mass spectra of vindorosine
    1964, Vol. 29, Issue 8, pp. 1913–1921 [Abstract]
  • J. Trojánek, O. Štrouf, K. Bláha, L. Dolejš and V. Hanuš
    On alkaloids. XII. Structure of vincaminorine and vincaminoreine
    1964, Vol. 29, Issue 8, pp. 1904–1912 [Abstract]
  • H. Bočková, J. Holubek and Z. Čekan
    Inhaltsstoffe des Ölbaums (Olea europea L.)
    1964, Vol. 29, Issue 6, pp. 1484–1491 [Abstract]
  • O. Štrouf and J. Trojánek
    On alkaloids. X. The structure of vincine
    1964, Vol. 29, Issue 2, pp. 447–456 [Abstract]
  • J. Trojánek, O. Štrouf, J. Holubek and Z. Čekan
    Über Alkaloide IX. Über die Struktur von Vincamin
    1964, Vol. 29, Issue 2, pp. 433–446 [Abstract]
  • J. Volke and J. Holubek
    Polarography of heterocyclic aromatic compounds. XV. Products of polarographic reduction of 4-cyanopyridine
    1963, Vol. 28, Issue 6, pp. 1597–1599 [Abstract]
  • B. K. Moza and J. Trojánek
    On alkaloids. VIII. Structure of vindorosine
    1963, Vol. 28, Issue 6, pp. 1427–1433 [Abstract]
  • B. K. Moza and J. Trojánek
    On alkaloids. VII. New alkaloids from Cataranthus roseus G. DON
    1963, Vol. 28, Issue 6, pp. 1419–1426 [Abstract]
  • J. Pospíšek and J. Trojánek
    Über ungesättigte quartäre Ammoniumverbindungen II. 1-(γ-Dimethylaminopropyl)-4,4-dimethylpiperidin-dimethohydroxyd
    1963, Vol. 28, Issue 2, pp. 463–468 [Abstract]
  • J. Trojánek and J. Hodková
    Über Alkaloide V. Isolierung von Vincamedin aus dem grossen Immergrün (Vinca major L.)
    1962, Vol. 27, Issue 12, pp. 2981–2985 [Abstract]
  • J. Trojánek, O. Štrouf, K. Kavková and Z. Čekan
    Über Alkaloide VI. Vincaminin und Vincinin, zwei neue Alkaloide aus Vinca minor L.
    1962, Vol. 27, Issue 12, pp. 2801–2807 [Abstract]
  • V. Schwarz, S. Heřmánek and J. Trojánek
    Steroid-Derivate XX. Einfluss des 17β-Substituenten auf die Brom-Additionsgeschwindigkeit an 3β-Acetoxy-Δ5-androsten-Derivate
    1962, Vol. 27, Issue 12, pp. 2778–2783 [Abstract]
  • J. Volke and J. Holubek
    Polarography of heterocyclic aromatic compounds. XIV. Reduction of ethylenic bond in 1,2-dipyridylethylenes
    1962, Vol. 27, Issue 8, pp. 1777–1789 [Abstract]
  • P. Horák, J. Holubek, V. Bumba and Z. Čekan
    Methoden zur Trennung von Naturstoffen V. Bestimmung von Morphin in Mohnkapselextrakten
    1962, Vol. 27, Issue 4, pp. 1037–1042 [Abstract]
  • J. Holubek and J. Volke
    Polarography of heterocyclic aromatic compounds. XIII. Polarographic fission of carbon-halogen bonds in monohalogenopyridines
    1962, Vol. 27, Issue 3, pp. 680–692 [Abstract]
  • J. Trojánek, H. Komrsová, J. Pospíšek and Z. Čekan
    Über N-alkylcamphidine
    1961, Vol. 26, Issue 11, pp. 2921–2932 [Abstract]
  • J. Trojánek, J. Pospíšek and Z. Čekan
    Über alkylderivate der stereoisomeren 2-aminocamphane
    1961, Vol. 26, Issue 10, pp. 2602–2611 [Abstract]
  • B. Pelc, S. Heřmánek and J. Holubek
    Über steroid-derivate XIII. Zur dehydrobromierung von 2,4-dibrom-3-keto-5α-androstan-derivaten in dimethylformamid
    1961, Vol. 26, Issue 7, pp. 1852–1861 [Abstract]
  • V. Schwarz, S. Heřmánek and J. Trojánek
    Steroid derivatives. XI. The effect of 3β-substituents on the rate of bromine addition to derivatives of Δ5-cholestene
    1961, Vol. 26, Issue 5, pp. 1438–1442 [Abstract]
  • J. Trojánek, K. Kavková, O. Štrouf and Z. Čekan
    Über Alkaloide IV. Über die Isolierung von Vincin, eines neuen Alkaloids aus Vinca minor L.
    1961, Vol. 26, Issue 3, pp. 867–873 [Abstract]
  • V. Schwarz and J. Trojánek
    Über Steroid-Derivate VIII. Quantitative Bestimmung der Doppelbindung in einigen Steroid-Verbindungen
    1961, Vol. 26, Issue 1, pp. 117–125 [Abstract]
  • J. Holubek and J. Volke
    Polarographie aromatischer heterocyclischer verbindungen X. Polarographische studie des systems 2,2'-pyridoin und 2,2'-pyridil
    1960, Vol. 25, Issue 12, pp. 3292–3305 [Abstract]
  • J. Holubek and J. Volke
    Polarography of aromatic heterocyclic compounds. IX. Polarographic reducibility of isomeric nitropyridines
    1960, Vol. 25, Issue 12, pp. 3286–3291 [Abstract]
  • R. Lukeš and J. Trojánek
    Darstellung von γ-amino- und γ-methylamino-butyraldehyddimethylacetal
    1960, Vol. 25, Issue 8, pp. 2248–2250 [Abstract]
  • J. Trojánek, O. Štrouf, K. Kavková and Z. Čekan
    Über alkaloide III. Neue alkaloide aus immergrün Vinca minor L.
    1960, Vol. 25, Issue 8, pp. 2045–2048 [Abstract]
  • R. Lukeš, J. Pliml and J. Trojánek
    Über den Hofmannschen abbau quaternärer basen und salze mit ungesättigten alkylen X. Thermische spaltung von 1,1-dimethyl-2-methylenpyrrolidiniumhydroxyd
    1959, Vol. 24, Issue 9, pp. 3109–3114 [Abstract]
  • R. Lukeš and Z. Veselý
    Synthetische versuche in der allolupinan-reihe IV. Eine zweite synthese des 4-hydroxymethylchinolicidins
    1959, Vol. 24, Issue 7, pp. 2318–2323 [Abstract]
  • R. Lukeš, J. Plešek and J. Trojánek
    Über die reduktionsprodukte des 1-methylpyrrols
    1959, Vol. 24, Issue 6, pp. 1987–1992 [Abstract]
  • J. Holubek and J. Volke
    Polarographische studie der spaltung des narcotolins
    1959, Vol. 24, Issue 5, pp. 1436–1443 [Abstract]
  • R. Lukeš and Z. Veselý
    Über die darstellung von δ-conicein
    1959, Vol. 24, Issue 3, pp. 944–949 [Abstract]
  • J. Trojánek, J. Hoffmannová, O. Štrouf and Z. Čekan
    Vincaminorin, ein neues alkaloid des immergrüns (Vinca minor L.)
    1959, Vol. 24, Issue 2, pp. 526–529 [Abstract]
  • J. Trojánek and J. Pospíšek
    1,3,4-Trimethylpyrrolidin
    1959, Vol. 24, Issue 1, pp. 307–309 [Abstract]
  • R. Lukeš, J. Trojánek and V. Lukeš
    Über den hofmannschen Abbau quaternärer Basen und Salze mit ungesättigten Alkylen VIII. Hexamethyl-trimethylen-bis-ammoniumhydroxyd
    1958, Vol. 23, Issue 2, pp. 321–325 [Abstract]
  • S. Heřmánek and J. Trojánek
    Synthese von trans6,7-oktahydroisochinolin
    1957, Vol. 22, Issue 4, pp. 1157–1161 [Abstract]
  • R. Lukeš and Z. Veselý
    Bemerkung zur bromcyanspaltung des N-methylpiperidins und des N-methylconiins
    1957, Vol. 22, Issue 2, pp. 638–640 [Abstract]
  • R. Lukeš and J. Trojánek
    Über den Hofmannschen abbau quaternärer basen und salze mit ungesättigten alkylen VII. 1,1-Dimethyl-Δ3-pyrroliniumhydroxyd und 1-phenyl-1,3,4-trimethyl-Δ3-pyrroliniumhydroxyd
    1957, Vol. 22, Issue 2, pp. 569–576 [Abstract]
  • R. Lukeš, J. Trojánek and K. Bláha
    Über die hydrierung der oxybenzoesäuren
    1955, Vol. 20, Issue 5, pp. 1136–1141 [Abstract]
  • R. Lukeš and J. Trojánek
    Über den Hofmann'schen abbau quaternärer basen und salze mit ungesättigten alkylen IV. Reduktion von 1-methyl-pyrrol
    1953, Vol. 18, Issue 5, pp. 648–653 [Abstract]
  • R. Lukeš and J. Trojánek
    Über den Hofmann'schen abbau quaternärer basen und salze mit ungesättigten alkylen III. 1,1-Dimethyl-pyrrolium-hydroxyd
    1953, Vol. 18, Issue 4, pp. 454–459 [Abstract]
  • R. Lukeš and J. Trojánek
    The Hofmann degradation of quaternary bases and salts containing unsaturated alkyl groups. II.
    1951, Vol. 16, pp. 603–610 [Abstract]
  • R. Lukeš and J. Trojánek
    Sur la décomposition de l'homoneurine par la chaleur
    1949, Vol. 14, pp. 688–692 [Abstract]